Combi15

COMBI 15 capsules PACKAGE INSERT

SCHEDULING STATUS: Nutritional supplement (Act 54/1972)

PROPRIETARY NAME (AND DOSAGE FORM): COMBI 15 capsules

COMPOSITION: Each capsule contains 25.8 mg of a probiotic mixture consisting of Lactobacillus acidophilus, Bifidobacterium bifidum and Bifidobacterium longum (in a lyophilized form), which yields in total a mixture of not less than 2 billion (2×109) viable cells.

PHARMACOLOGICAL ACTION: COMBI 15 capsules comprise a mixture of lyophilized lactic acid bacteria namely, Lactobacillus acidophilus, Bifidobacterium bifidum and Bifidobacterium longum which are natural inhabitants of the human intestines. COMBI 15 is administered to restore the naturally occurring bacterial intestinal flora destroyed during antibiotic therapy. Antibiotic therapy inhibits the normal flora from re-establishing itself. Through competition for bacterial adhesion sites on the intestinal epithelial surfaces, the lactic acid bacteria contained in COMBI 15 inhibit the pathogenic bacteria from establishing themselves. INDICATIONS: COMBI 15 capsules: “When ingested on a regular basis, probiotics should improve or normalise the microbial balance in the human intestines and thereby improve the functioning of the digestive tract”

• Assist in the restoration of the naturally occurring bacterial intestinal flora during
  antibiotic therapy.
• Assist in the acute treatment of antibiotic-induced diarrhoea.
• Assist in the stimulation of the immune system.

CONTRA-INDICATIONS: None known.

DOSAGE AND DIRECTIONS FOR USE:
In conjunction with antibiotic therapy: 1 capsule to be taken 3 times per day with water preferably on an empty stomach, 30 minutes before meals.

SIDE-EFFECTS AND SPECIAL PRECAUTIONS: Large doses may cause loose stools in some individuals.

KNOWN SYMPTOMS OF OVERDOSAGE AND PARTICULARS OF ITS TREATMENT: Loose stools whereupon the administration of COMBI 15 should be discontinued temporarily.

IDENTIFICATION: White gelatine capsules containing white to cream coloured, granular material with a slight lactic acid smell.

PRESENTATION: 15 capsules in a blister pack, packed in a box.

STORAGE INSTRUCTIONS: Store in a cool, dry place below 25°C

KEEP OUT OF REACH OF CHILDREN